Brain perfusion magnetic resonance imaging using pseudocontinuous arterial spin labeling in 314 dogs and cats

• DOI: 10.1111/jvim.16215
• Publication Date: 2021-07-22T07:31:41Z
• Authors: Anne‐Cécile Hoffmann; Yannick Ruel; Kirsten Gnirs; Stella Papageorgiou; Luca Zilberstein; Sarah Nahmani; Nathalie Boddaert; Hugues Gaillot
• Keywords: Foramen magnum; Arterial spin labeling

Abstract Background Arterial spin labeling (ASL) is a noninvasive brain perfusion magnetic resonance imaging (MRI) technique that has not been assessed in clinical veterinary medicine. Hypothesis/Objectives To test the feasibility of ASL using 1.5 Tesla scanner and provide recommendations for optimal quantification cerebral blood flow (CBF) dogs cats. Animals Three hundred fourteen prospectively selected client‐owned Methods Each animal underwent MRI including morphological sequences ≥1 different sites postlabeling delays (PLD). Calculated success rates were compared. The CBF was quantified animals had morphologically normal results parameters optimization investigated. Results easily implemented with an overall rate 95% MRI. Technical included (a) positioning slab at foramen magnum (b) PLD 1025 ms cats <7 kg, 1525 7 to 38 2025 >38 kg. In 37 dogs, median cortex thalamic nuclei 114 95 mL/100 g/min, respectively. 28 cats, 113 Conclusions Clinical Importance Our survey ASL‐MRI demonstrated Tesla, suggested technical provided values should be helpful characterization various diseases