Clinical, laboratory and ultrasonographic findings differentiating low‐grade intestinal T‐cell lymphoma from lymphoplasmacytic enteritis in cats

• DOI: 10.1111/jvim.16272
• Publication Date: 2021-10-23T07:52:12Z
• Authors: Valérie Freiche; Julien Fages; Mathieu Victor Pa...; Julie Bruneau; Lucile Couronné; Alexander J. German; Dominique Penninck; Olivier Hermine
• Keywords: Lymphoplasmacytic Lymphoma; Abdominal ultrasonography; Histology

Low-grade intestinal T-cell lymphoma (LGITL) is the most common neoplasm in cats. Differentiating LGITL from lymphoplasmacytic enteritis (LPE) challenging because clinical signs, laboratory results, diagnostic imaging findings, histology, immunohistochemistry, and clonality features may overlap.To evaluate possible discriminatory clinical, ultrasonographic to differentiate LPE.Twenty-two cats diagnosed with 22 LPE based upon lymphoid clonality.Prospective, cohort study. Cats presented signs consistent or were enrolled prospectively. All data contributing evaluation was recorded.A 3-variable model (P < .001) consisting of male sex = .01), duration polyphagia .03) a 2-variable including rounded jejunal lymph node abdominal effusion .04) both helpful LPE.Most results are similar between LPE. However, sex, longer might help clinicians distinguish On ultrasonography, node, presence (albeit small volume) tended be more prevalent LGITL. definitive diagnosis requires comprehensive histopathologic phenotypic assessment.