Cytologic Evaluation as a Diagnostic Tool to Differentiate Adrenocortical Tumors and Pheochromocytomas

• DOI: 10.1111/jvim.70021
• Publication Date: 2025-03-30T23:42:45Z
• Authors: Hunter J. Piegols; Rachel W. Williams; Nirali Pathak; Laura E. Selmic; Giovanni Tremolada; Russell Sakacs; Laurie Millward; Janis Lapsley
• Keywords: Adrenocortical adenoma

ABSTRACT Background The utility of cytologic evaluation to distinguish adrenocortical tumors and pheochromocytomas in dogs has not been thoroughly investigated, partly because the perceived risks procedure. Objectives Report test characteristics fine needle aspiration (FNA) for differentiation dogs. Complications associated with FNA also were recorded. Animals Thirty‐eight 40 adrenal that had performed before adrenalectomy included study from three institutions. Tumors 17 pheochromocytomas, 21 tumors, 1 concurrent adenoma pheochromocytoma, malignant neoplasm. Results Of aspirations performed, 35 (87.5%) a predominant cell type identified therefore considered diagnostic quality. these, 30 (85.7%) correlated final histopathological diagnosis. When all samples included, sensitivity 77.3%, specificity 76.5%, positive predictive value 81.0%, negative 72.2%, accuracy 76.9% identifying tumors. For these values 95.2%, 92.8%, 80.0%, 84.5%, respectively. Six (15.9%) self‐limiting complications Conclusion Clinical Importance Fine low complication rate can help differentiate pheochromocytomas. Thus, should be allow more individualized treatment affected