New ICA criteria for the diagnosis of acute kidney injury in cirrhotic patients: can we use an imputed value of serum creatinine?

• DOI: 10.1111/liv.12852
• Publication Date: 2015-04-21T07:03:14Z
• Authors: Silvia Rosi; Salvatore Piano; Anna C. Frigo; Filippo Morando; Silvano Fasolato; Marta Cavallin; Elisabetta Gola; Antonietta Romano; Sara Montagnese; Antonietta Sticca; Angelo Gatta; Paolo Angeli
• Keywords: Decompensation

The new International Club of Ascites diagnostic criteria to diagnose acute kidney injury at hospital admission suggests the possibility using a presumed baseline serum creatinine, defined as last least two stable creatinine values during 3 months. Nevertheless, lack such value still remains. In these patients, KDIGO suggest use an inverse application MDRD equation assuming that glomerular filtration rate is 75 ml/min per 1.73 m(2) (imputed creatinine). We tested accuracy this approach detect in patients with decompensated cirrhosis and <1.5 mg/dl.We analysed 213 hospitalized for decompensation cirrhosis. At admission, was estimated creatinine-based equations measured by inulin clearance. A diagnosis made imputed baseline.The AKI based on identified only 20.1% ≤60 ml/min/1.73 without any predictive 90-day survival.In ascites mg/dl their records, not accurate.