Population genomic footprints of selection and associations with climate in natural populations of Arabidopsis halleri from the Alps

• DOI: 10.1111/mec.12521
• Publication Date: 2013-09-14T10:52:53Z
• Authors: Martin C. Fischer; Christian Rellstab; Andrew Tedder; Stefan Zoller; Felix Gugerli; Kentaro K. Shimizu; Rolf Holderegger; Alex Widmer
• Keywords: Outcrossing; Local adaptation; Candidate gene

Natural genetic variation is essential for the adaptation of organisms to their local environment and changing environmental conditions. Here, we examine genomewide patterns nucleotide in natural populations outcrossing herb Arabidopsis halleri associations with climatic among Alps. Using a pooled population sequencing (Pool-Seq) approach, discovered more than two million SNPs five identified highly differentiated genomic regions using FST -based analyses. We tested only most strongly nonredundant set factors partial Mantel tests identify topo-climatic that may underlie observed footprints selection. Possible functions genes showing signatures selection were by Gene Ontology analysis. found 175 be associated one or factors. Of these, 23.4% had unknown functions. Genetic four candidate was site water balance solar radiation, functional annotations congruent these Our results provide perspective on distribution adaptive plant from diverse heterogeneous alpine environment.