Candida infections in paediatrics: Results from a prospective single‐centre study in a tertiary care children's hospital

• DOI: 10.1111/myc.12570
• Publication Date: 2016-09-29T09:44:12Z
• Authors: Alessio Mesini; Roberto Bandettini; Ilaria Caviglia; Francesca Fioredda; Loredana Amoroso; Maura Faraci; Girolamo Mattioli; Giorgio Piaggio; Francesco M. Risso; Andrea Moscatelli; Anna Loy; Elio Castagnola
• Keywords: Etiology; Isolation; Tertiary care

To describe the epidemiology of invasive Candida infection in a tertiary care paediatric hospital. Prospective single-centre survey on all strains isolated from normally sterile fluids and urines period 2005-2015 . A total 299 ICI were documented 262 patients. Urinary tract represented most frequent diagnosis (62%), followed by fungaemia (34%) peritonitis (4%). Fungaemia was children with cancer (59%) or low birth weight neonates (61%), while urinary infections more patients malformation. C.albicans frequently species (60%) compared C. non-albicans, but differences present according to site isolation underlying conditions. Overall 90-day mortality 7%, 13% fungaemias, 8% 2% infections. The rates increased during study period. Invasive is diagnosed increasing frequency children. Site aetiology are related presence underlying, favouring Mortality not negligible, especially specific