Depression, young age, chronic marijuana use, and interepisodic symptoms predict psychological distress in patients with cyclic vomiting syndrome

• DOI: 10.1111/nmo.13245
• Publication Date: 2017-11-20T06:06:41Z
• Authors: Tatyana Taranukha; Vishnu Charan Sur...; Alex Seamon; Natasha Sahr; Aniko Szabo; Thangam Venkatesan
• Keywords: Depression; Psychological Distress

Abstract Background Cyclic vomiting syndrome ( CVS ) is often triggered by stress. Patients report high degrees of psychological distress due to , but there limited data on factors associated with distress. We sought determine the degree and its correlation clinical characteristics in . Methods The Brief Symptom Inventory BSI ), a validated tool distress, was administered prospectively patients. control population consisted 719 normal subjects. Student's t test used compare means, logistic regression analysis performed identify predictors GSI score ≥63, indicating Scores for were calculated using maximum likelihood estimate model called DAME (depression, age 25‐35, chronic marijuana use, interepisodic GI symptoms). Key Results Of 87 patients, 60% female, 92% caucasian, mean 37 years. Forty‐one percent patients had highest scores somatization. Independent included d epression, young ge (25‐35 years), m arijuana inter e pisodic dyspepsia (called score). A ≥7 accurately predicted >88% Conclusions & Inferences Psychological common can be our proposed score. Whether cause or an effect needs determined. Addressing potentially improve overall healthcare outcomes