Global analysis of sumoylation function reveals novel insights into development and appressorium‐mediated infection of the rice blast fungus

• DOI: 10.1111/nph.15141
• Publication Date: 2018-04-17T01:52:30Z
• Authors: Caiyun Liu; Zhigang Li; Junjie Xing; Jun Yang; Zhao Wang; Hong Zhang; Deng Chen; You‐Liang Peng; Xiao‐Lin Chen
• Keywords: Appressorium

Summary Protein post‐translational modifications play critical roles in cellular processes, development and stress response. The small ubiquitin‐like modifier ( SUMO ) to proteins is one of the essential eukaryotes, but its function remains largely unknown plant pathogenic fungi. We present a comprehensive analysis combined with proteomic, molecular approaches explore sumoylation model fungal pathogen, Magnaporthe oryzae . found pathway plays key colony growth, conidia formation virulence host, as well cell‐cycle‐related phenotypes. Sumoylation also involved responding different stresses. Affinity purification identified 940 putative substrates, many which were reported be development, response infection. Interestingly, four septins shown sumoylated. Mutation consensus sites each septin all resulted reduced host dislocation appressoria. Moreover, extracellular secretion effector proteins. Our study on functions provides novel insight into infection rice blast fungus.