TGFam‐Finder: a novel solution for target‐gene family annotation in plants

• DOI: 10.1111/nph.16645
• Publication Date: 2020-05-11T19:14:29Z
• Authors: Seungill Kim; Kyeongchae Cheong; Jieun Park; Myung‐Shin Kim; Jihyun Kim; Min‐Ki Seo; Geun Young Chae; Min Jeong Jang; Hyunggon Mang; Sun‐Ho Kwon; Yong‐Min Kim; Namjin Koo; Cheol Woo Min; Kwang‐Soo Kim; Nuri Oh; Ki‐Tae Kim; Jongbum Jeon; Hyunbin Kim; Yoon‐Young Lee; Kee Hoon Sohn; Honour C. McCann; Sang‐Kyu Ye; Sun Tae Kim; Kyung‐Soon Park; Yong‐Hwan Lee; Doil Choi
• Keywords: Gene Annotation; Gene prediction

Summary Whole‐genome annotation error that omits essential protein‐coding genes hinders further research. We developed Target Gene Family Finder ( TGFam‐Finder ), an alternative tool for the structural of containing target domain(s) interest in plant genomes. took considerably reduced run‐time and improved accuracy compared to conventional tools. Large‐scale re‐annotation 50 genomes identified average 150, 166 86 additional far‐red‐impaired response 1, nucleotide‐binding leucine‐rich‐repeat, cytochrome P450 genes, respectively, were missed previous annotations. detected significantly higher number translated new annotations using mass spectrometry data from seven species along with gene models can provide optimized platform comprehensive functional, comparative, evolutionary studies plants.