A Phytophthora capsici RXLR effector targets and inhibits the central immune kinases to suppress plant immunity

• DOI: 10.1111/nph.17573
• Publication Date: 2021-06-22T18:47:38Z
• Authors: Xiangxiu Liang; Yazhou Bao; Meixiang Zhang; Dandan Du; Shaofei Rao; Yixin Li; Xiaodan Wang; Guangyuan Xu; Zhaoyang Zhou; Danyu Shen; Qin Chang; Weiwei Duan; Gan Ai; Jie Lu; Jian‐Min Zhou; Daolong Dou
• Keywords: Oomycete; Phytophthora capsici; Plant Immunity; Subfamily

Summary Receptor‐like cytoplasmic kinase subfamily VII (RLCK‐VII) proteins are the central immune kinases in plant pattern‐recognition receptor (PRR) complexes, and they orchestrate a complex array of defense responses against bacterial fungal pathogens. However, role RLCK‐VII plant–oomycete pathogen interactions has not been established. Phytophthora capsici is notorious oomycete that infects many agriculturally important vegetables. Here, we report identification RXLR25, an RXLR effector required for virulence P . In planta expression RXLR25 significantly enhanced plants’ susceptibility to Microbial pattern‐induced activation Arabidopsis was severely impaired by RXLR25. We further showed interacts with proteins. Using nine rlck‐vii high‐order mutants, observed RLCK‐VII‐6 RLCK‐VII‐8 members resistance P. The specifically culture filtrate (CF)‐induced responses. directly targets such as BIK1, PBL8, PBL17 inhibits phosphorylation RLCK‐VIIs suppress downstream This study identified key factor , results revealed importance interactions.