Histone acetyltransferase TaHAG1 interacts with TaPLATZ5 to activate TaPAD4 expression and positively contributes to powdery mildew resistance in wheat

• DOI: 10.1111/nph.18372
• Publication Date: 2022-07-14T05:36:27Z
• Authors: Na Song; Jingchen Lin; Xingbei Liu; Zehui Liu; Debiao Liu; Wei Chu; Jinpeng Li; Yongming Chen; Shumin Chang; Qun Yang; Xiaoyu Liu; Weilong Guo; Mingming Xin; Yingyin Yao; Huiru Peng; Zhongfu Ni; Chaojie Xie; Qixin Sun; Zhaorong Hu
• Keywords: Histone acetyltransferase

Summary Plants have evolved a two‐branched innate immune system to detect and cope with pathogen attack, which are initiated by cell‐surface intracellular receptors leading pattern‐triggered immunity (PTI) effector‐triggered (ETI), respectively. A core transducer including PAD4‐EDS1 node is proposed as the convergence point for two‐tiered in conferring immunity. However, transcriptional regulatory mechanisms controlling expression of these key transducers remain largely unknown. Here, we identified histone acetyltransferase TaHAG1 positive regulator powdery mildew resistance wheat. regulates gene TaPAD4 promotes SA reactive oxygen species accumulation accomplish Bgt infection. Moreover, overexpression CRISPR‐mediated knockout validate its role wheat resistance. Furthermore, physically interacts TaPLATZ5, plant‐specific zinc‐binding protein. TaPLATZ5 directly binds promoter together potentiate increasing levels H3 acetylation. Our study revealed transcription acts an epigenetic modulator that confers through activating between PTI ETI, could be effective genetic improvement disease other crops.