The dynamics of the oral microbiome and oral health among patients receiving clear aligner orthodontic treatment

• DOI: 10.1111/odi.13175
• Publication Date: 2019-08-16T12:57:47Z
• Authors: Rui Zhao; Renhuan Huang; Hu Long; Yan Li; Meiya Gao; Wenli Lai
• Keywords: Fusobacteria; Oral Microbiome; Prevotella

This 6-month prospective clinical study assessed the impacts of Invisalign appliances on oral bacterial community and health patients.Salivary samples were obtained from twenty-five adult patients receiving aligner treatment before (Group B) at a follow-up P). The composition each sample was determined using Illumina MiSeq sequencing 16S rRNA. Intra- intergroup biodiversity analyzed. Clinical periodontal parameters daily hygiene habits recorded.Reduction in plaque, increased brushing frequency, decreased dessert intake observed Group P compared with that B. A total 1,853,952 valid reads 50 salivary samples, 37,904 sequences per sample. No significant differences detected intra- comparisons between two groups. By clustering, 8,885 OTUs identified categorized into six major phyla: Firmicutes, Proteobacteria, Bacteroidetes, Fusobacteria, Actinobacteria, Candidate_division_TM7_norank. At genus level, B, demonstrated significantly Bacillus abundance Prevotella abundance.Our results suggested general microbial structure did not change had beneficial awareness during first months treatment. Hence, basis this study, it appears induce deterioration nor changes communities, assuming detailed instructions for both teeth aligners provided.