A multicenter study of oral sarcomas in Brazil

• DOI: 10.1111/odi.13211
• Publication Date: 2019-10-12T14:13:06Z
• Authors: Waldner Ricardo S...; Lucas Lacerda de ...; Flávia Sirotheau ...; Daniel Cavallero ...; Davi Lavareda Corrêa; Cinthia Verónica ...; Márcio Ajudarte L...; Alan Roger Santos...; Pablo Agustin Vargas; Bruno Augusto Ben...; Mário Romañach; Ricardo Santiago ...; Sara Ferreira dos...; Aline Carvalho Ba...; Elismauro Francis...; Décio dos Santos ...; Rogério Gondak; Danyel Elias da C...; Cassiano Nonaka; Jean Nunes dos Sa...; Tatiana Nayara Li...; Jeconias Câmara; Fábio Ramôa Pires; Lélia Batista de ...; Manoela Domingues...; Oslei Paes de Alm...; Felipe Paiva Fonseca; Hélder Antônio Re...
• Keywords: Adult; Aged, 80 and over; Male; Osteosarcoma; Adolescent; Biopsy; Sarcoma; Middle Aged; 3. Good health; Young Adult; 03 medical and health sciences; Cross-Sectional Studies; 0302 clinical medicine; Child, Preschool; Humans; Female; Mouth Neoplasms; Child; Sarcoma, Kaposi; Brazil; Aged; Retrospective Studies

AbstractObjectivesThe aim of this study was to investigate the prevalence of oral sarcomas from geographic regions of Brazil.Materials and methodsA cross‐sectional study was conducted on biopsies obtained from January 2007 to December 2016 at twelve Brazilian oral and maxillofacial pathology centres. Gender, age, evolution time, clinical aspects, tumour location, tumour size at diagnosis, radiographic aspects and histopathological diagnosis were evaluated. Data were analysed using descriptive statistical methods.ResultsFrom 176,537, a total of 200 (0.11%) oral sarcomas were reported, and the most prevalent were osteosarcomas (74 cases; 37%) and Kaposi's sarcomas (52 cases; 26%). Males were more affected than females at a mean age of 32.2 years old (range of 3–87 years). The most common symptoms were swelling¸ localised pain and bleeding at a mean evolution time of 5.14 months (range <1–156 months). The lesions were mostly observed in the mandible (90 cases; 45%), with a mean tumour size of 3.4 cm (range of 0.3–15 cm). Radiographically, the lesions presented a radiolucent aspect showing cortical bone destruction and ill‐defined limits.ConclusionsOral sarcomas are rare lesions with more than 50 described subtypes. Osteosarcomas and Kaposi's sarcomas were the main sarcomas of the oral cavity in Brazil.