Changes in visual cortical function in moderately myopic patients: a functional near‐infrared spectroscopy study

• DOI: 10.1111/opo.12921
• Publication Date: 2021-11-19T08:46:05Z
• Authors: Ying Zhang; Xiao Lin; Ailing Bi; Ning Cao; Tingyu Zhang; Sha Wang; Ying Wen; Hongsheng Bi
• Keywords: Emmetropia; Functional near-infrared spectroscopy

Abstract Purpose To investigate haemoglobin oxygenation in the visual cortex of myopic patients using functional near‐infrared spectroscopy (fNIRS). Methods The experiment consisted two parts. Part 1 examined changes before and after refractive correction patients. Subjects were divided into normal controls, uncorrected corrected myopes. 2 caused by lens‐induced myopia subjects, whether this activity recovered a period rest. Here, subjects three groups: emmetropes, rest group. group completed test with eye following lens removal 5 min stimulus was black white checkerboard. fNIRS used to detect oxyhaemoglobin content within cortex. original data analysed MATLAB obtain β values (the cortical response task); these calculate Δβ, which represents degree change oxygenated stimulation. Results Δβ value measured each single channel or only region interest (ROI) significantly higher emmetropic control than After optical correction, responses approached those emmetropes not different. If induced imposing defocus positive lenses, decline observed similar that Activity lenses removed. Conclusions Myopic reduced level cortex, but could be restored correction.