Evaluation of a Unique Defibrillation Unit with Dual‐Vector Biphasic Waveform Capabilities: Towards a Miniaturized Defibrillator

• DOI: 10.1111/pace.12979
• Publication Date: 2016-12-19T06:52:48Z
• Authors: HIDEO OKAMURA; CHRISTOPHER V. DE...; AMMAR M. KILLU; EMILY J. GILLES; JASON TRI; ROSHINI ASIRVATHAM; DEJAE J. LADEWIG; SCOTT H. SUDDENDORF; JOANNE M. POWERS; CHRISTINA M. WOOD...; PETER D. GRAY; DOUGLAS M. RAYMOND; SHELLEY J. SAVAGE; WALTER T. SAVAGE; CHARLES J. BRUCE; SAMUEL J. ASIRVATHAM; PAUL A. FRIEDMAN
• Keywords: Defibrillation threshold; Fibrillation

Background Automated external defibrillators can provide life‐saving therapies to treat ventricular fibrillation. We developed a prototype unit that deliver unique shock waveform produced by four independent capacitors is delivered through two vectors, with the rationale of providing more robust pathways during emergent defibrillation. describe initial testing and feasibility this defibrillation unit, features which may enable downsizing current defibrillator devices. Methods tested our in large animal models (two canine swine) under general anesthesia. Experimental thresholds (DFT) were obtained delivery pulse via dual‐vector pathway pads (placed across chest). DFTs measured compared those commercially available biphasic (Zoll M series, Zoll Medical, Chelmsford, MA, USA) different vectors. Shocks after 10 seconds stable fibrillation output characteristics outcome recorded. Each series used step‐down failure protocol define threshold. Results A total 96 shocks animals. In comparison single‐vector, shock, energy required for successful using did not differ significantly (P = 0.65). Conclusions Our early findings support approach. This warrants further study leverage concept work toward miniaturized, portable system.