Long‐term outcomes of pulmonary vein isolation using second‐generation cryoballoon during atrial fibrillation ablation

• DOI: 10.1111/pace.13721
• Publication Date: 2019-05-20T08:16:09Z
• Authors: Ugur Canpolat; Duygu Kocyigit; Muhammed Ulvi Yalcin; Cem Coteli; Yusuf Ziya Sener; Metin Oksul; Kadri Murat Gürses; Banu Evranos; Hikmet Yorgun; Kudret Aytemir
• Keywords: Interquartile range; Atrial tachycardia

Abstract Background Currently available second‐generation cryoballoon (CB2) is accepted as an effective and safe tool for pulmonary vein isolation (PVI). Although much more data exist about 1‐year outcomes of CB2 ablation, on long‐term are scarce. Objective We aimed to assess the PVI using in a large‐scale symptomatic atrial fibrillation (AF) population at our tertiary referral center. Methods In this nonrandomized prospective observational study, total 486 patients with paroxysmal (71%) or persistent (29%) AF who underwent index hospital between January 2013 June 2017 were enrolled. Atrial tachyarrhythmia (ATa)‐free survival was defined absence AF, flutter, tachycardia recurrence ≥30 s following 3 months blanking period. Predictors evaluated by univariate multivariate Cox proportional hazards regression models. Results Acute procedural success rate 99.8% (1898/1902 PVs). Mean fluoroscopy time 64.9 ± 9.2 12.1 2.6, respectively. At median 39 (interquartile range: 26‐56) follow‐up, ATa‐free 78.6% after single procedure (280/345 [81.2%] vs. 102/141 [72.3%] P = .019) 84.4% mean 1.48 0.42 ablations. analysis showed that left atrium diameter, duration history, early ATa found independent predictors late recurrence. Phrenic nerve palsy observed 17 (3.5%) patients. Conclusions CB2‐based maintain sinus rhythm significant proportion acceptable complication follow‐up.