Patient quality of life following induction of oral immunotherapy for food allergy

• DOI: 10.1111/pai.12528
• Publication Date: 2015-12-18T05:14:40Z
• Authors: Na'ama Epstein Rigbi; Yitzhak Katz; Michael R. Goldberg; Michael B. Levy; Liat Nachshon; Arnon Elizur
• Keywords: Oral immunotherapy; Oral food challenge

Abstract Background Patient quality of life improves following successful completion oral immunotherapy ( OIT ), but the process itself might have undesirable effects. We aimed to evaluate patient initial induction. Methods The Hebrew version Food Allergy Quality Life Questionnaire‐Parental Form FAQLQ ‐ PF ) was validated and administered parents children first week for food allergy (n = 119). demographics clinical history as well course induction were reviewed. Results Pre‐ severity allergy, defined reactions due accidental exposure allergenic (anaphylactic reactions, p 0.017; epinephrine use, 0.049; emergency room referrals 0.003; hospital admissions, 0.015) a lower number tolerated doses during induction, reflective maximal dose different allergens (p 0.011) associated with worse total scores. pre‐OIT remained significantly score on multivariate analysis 0.016 0.005, respectively). correlation between scores moderate–strong primarily in aged 6–12 years (Total score, r −0.41, 0.001; Emotional Impact −0.42, Anxiety, −0.38, 0.002; Social Dietary Limitations, −0.33, 0.009). Conclusions reaction affects both preschool school‐aged food‐allergic children. In contrast, is indices years.