AAAAI–EAACI PRACTALL: Standardizing oral food challenges—2024 Update

• DOI: 10.1111/pai.14276
• Publication Date: 2024-11-19T11:33:14Z
• Authors: Hugh A. Sampson; Stefania Arasi; Henry T. Bahnson; Barbara Ballmer‐W...; Kirsten Beyer; Carsten Bindslev‐...; J. Andrew Bird; Katarina Blumchen; Carla Davis; Motohiro Ebisawa; Anna Nowak‐Wegrzyn; Nandinee Patel; Rachel L. Peters; Scott Sicherer; Jonathan Spergel; Paul J. Turner; Noriyuki Yanagida; Philippe A. Eigen...
• Keywords: Clinical immunology; Oral food challenge; Egg allergy; Peanut Allergy

This common statement of the American Academy Allergy, Asthma and Immunology (AAAAI) The European Allergy Clinical (EAACI) provides an update 2012 published guidelines on food challenges. equally address challenges in research clinical settings. They first diagnostic tests which can guide decision to conduct a challenge. Safety is prime, various procedures safety issues as well medications potentially involved are extensively discussed. Challenges suggested be conducted with semi-logarithmic incremental doses based protein content, typically for IgE-mediated allergy intervals 20-30 min between doses. Specific protocols other types reactions such atopic dermatitis or gastrointestinal detailed separately. Proper stopping criteria essential order reduce risk false-positive diagnoses, but also severe reactions. recommend "go on," "stop," "observation." These revised will clearly provide much needed guidance continue evolve new needs field allergy.