Perioperative factors associated with persistent opioid use after extensive abdominal surgery in children and adolescents: A retrospective cohort study

Male Pain, Postoperative Adolescent Cytoreduction Surgical Procedures Hyperthermia, Induced Drug Administration Schedule Time 3. Good health Analgesics, Opioid Cohort Studies 03 medical and health sciences 0302 clinical medicine Abdominal Neoplasms Abdomen Prevalence Humans Female Chronic Pain Child Perioperative Period Retrospective Studies
DOI: 10.1111/pan.13386 Publication Date: 2018-05-12T12:25:16Z
ABSTRACT
Summary Background In adults, preoperative opioid use and higher perioperative consumption have been associated with odds of persistent after surgery. There are limited data on the prevalence factors major oncologic surgery in children. Aims this study, we sought to determine development a group children adolescents who had undergone cytoreductive hyperthermic intraperitoneal chemotherapy. Methods A retrospective study patients ≤19 years age was performed. Univariable logistic regression used assess postdischarge up 6 months. Results Eighty‐six were identified. The median 12 years, 43% female. proportion over immediate 3, 6, 24 months 54/77 (70%), 18/51 (35%), 13/45 (29%), 3/24 (13%), respectively. daily average in‐patient pain scores subsequently developed (estimated difference 0.5, 95% confidence interval [ CI ]: 0.3, 0.8, P < .01). Furthermore, postoperative greater subsequent (odds ratio 1.03, : 1.00, 1.07, = .05). Conclusion surgery,
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