Diaper dermatitis prevalence and severity: Global perspective on the impact of caregiver behavior

• DOI: 10.1111/pde.14047
• Publication Date: 2019-12-03T02:07:01Z
• Authors: Andrew N. Carr; Thomas DeWitt; Michael J. Cork; Lawrence F. Eiche...; Regina Fölster‐Holst; Daniel Hohl; Alfred T. Lane; Amy Paller; Larry Pickering; Alain Taieb; Tao Y. Cui; Zi G. Xu; Xeumin Wang; Susanna Brink; Yeuqing Niu; Julie Ogle; Mauricio Odio; Roger D. Gibb
• Keywords: Diaper Dermatitis; Intertriginous; Skin Barrier; Transepidermal water loss

Abstract Objectives To compare prevalence and severity of diaper dermatitis (DD) in infants toddlers (babies) across three countries (China, USA, Germany), including diapered skin measures caregiver practices. Methods A cross‐sectional study 1791 babies (~600 from each country) was recruited at clinical site. Based on regional toilet‐training habits, exclusively diaper‐wearing were between ages 2‐8 months China 2‐18 the USA Germany. DD measured, as well pH, transepidermal water loss (TEWL), relative humidity (RH) region. Caregiver habits collected via a questionnaire included information hygienic Results Diaper highest perianal area, followed by intertriginous, genital, buttock regions. In general, significantly lower China, Germany, intermediate USA. This rank ordering geography also observed baby age months. The associated with pH TEWL decreased RH diaper. Chinese caregivers had rate prophylactic topical product usage, most robust cleaning lack cleansing after urine‐only changes, spent least time an overnight Conclusions These data suggest behaviors use products, thorough stooling reduced are less DD, superficial enhanced barrier.