Patients with schizophrenia have impaired muscle force‐generating capacity and functional performance

• DOI: 10.1111/sms.13526
• Publication Date: 2019-07-30T01:08:36Z
• Authors: Mona Nygård; Mathias Forsberg ...; Ragnhild Bjerkem ...; Joshua Landen Taylor; Solveig Klæbo Reitan; Ismail Cüneyt Güzey; Gunnar Morken; Einar Vedul‐Kjelsås; Eivind Wang; Jørn Heggelund
• Keywords: Stair climbing; Climbing

Patients with schizophrenia have impaired physical health. However, evidence of how skeletal muscle force-generating capacity (FGC), a key component functional performance, may contribute to the impairment is scarce. Thus, aim this study was investigate patient groups' FGC and its association performance. Leg-press assessed along battery performance tests in 48 outpatients (28 men, 34 ± 10 years; 20 women, 36 12 years) spectrum disorder (ICD-10, F20-29), compared healthy age- gender-matched references. Results revealed reduced one-repetition maximum (1RM) men (-19%, P < .01) trend toward reduction women (-13%, = .067). The ability develop force rapidly also (men: -30%; women: -25%, both .01). scored worse than references on all (stair climbing: -63%; 30-second sit-to-stand (30sSTS): -48%; six-minute walk test (6MWT): -22%; walking efficiency: -14%; unipedal stance eyes open: -20% closed: -73%, 1RM correlated 6MWT (r .45), stair climbing -.44), 30sSTS .43), efficiency .26), open .33) closed .01. Rapid development .54), -.49), .44) .51), In conclusion, are patients should be recognized as important aspects Resistance training aiming improve these components considered an part clinical treatment.