Endurance exercise training volume is not associated with progression of coronary artery calcification

• DOI: 10.1111/sms.13643
• Publication Date: 2020-02-26T02:06:09Z
• Authors: Øyunn Kleiven; Magnus F. Bjørkav...; Torbjørn Omland; Kristin M. Aakre; Vidar Frøysa; Christine B. Erevik; Ole J. Greve; Tor H. Melberg; Bjørn Auestad; Øyvind Skadberg; Thor Edvardsen; Stein Ørn
• Keywords: Agatston score; Coronary Calcium Score; Endurance Training

Recent cross-sectional studies have suggested a dose-dependent relationship between lifelong exposure to physical activity and the burden of calcified coronary artery disease (CAD). No longitudinal addressed this concern.Exercise volume is associated with progression calcium (CAC), defined as ≥10 units increase in CAC score.Sixty-one recreational athletes who were assessed by computed tomography angiography (CCTA) part NEEDED 2013/14 study re-assessed 4-5 years later, 2018.Subjects 45.9 ± 9.6 old at inclusion, 46 (74%) male. Between 2013 2018, participants reported median 5 (range: 0-20, 25th-75th percentile: 4-6) hours high-intensity exercise per week. None included subjects smoked during follow-up. At 21 (33%) had calcifications. On follow-up CCTA 15 (25%) progressive calcification (≥10 Agatston CAC). These older (53 9 vs 44 old, P = .002) higher levels low-density lipoprotein baseline (3.5 (2.9-4.3) 2.9 (2.3-3.5) mmol/L, .031) compared stable condition. was found endurance training week calcification. In multiple regression analysis, age only significant predictors CAC.No middle-aged athletes.