Distinguishing rosacea from sensitive skin by reflectance confocal microscopy

• DOI: 10.1111/srt.12851
• Publication Date: 2020-03-17T05:19:26Z
• Authors: Yafeng Ma; Lulu Li; Jia Chen; Tian Chen; Chao Yuan
• Keywords: Parakeratosis

Abstract Background The updated standard classification and pathophysiology of rosacea have provided clear meaningful evaluation parameters; however, differentiating from sensitive skin (SS) remained an obstacle for dermatologists around the world, especially in China. Herein, we aimed to find a better characteristic distinguish SS by using reflectance confocal microscopy (RCM). Method Forty patients 143 healthy subjects were recruited this study. Firstly, questionnaire lactic acid sting test conducted among subjects. Next, two major groups divided out, including group (40 subjects) normal control (NS, 60 subjects). cutaneous structures face fossa cubitalia imaged RCM. Results We found that more parakeratosis, honeycomb pattern, spongiform edema, dermal papillae ( P < .05) than NS group, whereas there no significant differences, group. Strikingly, larger depth pattern .05). But, epidermal thickness did not differ groups. There was also difference structure between Conclusion From RCM images papillae, might be faithful tool superficial patients, may provide new method evaluating development although it failed effectively.