Outcomes and prognostic factors in 70 non‐survivors and 595 survivors with COVID‐19 in Wuhan, China

• DOI: 10.1111/tbed.13969
• Publication Date: 2020-12-31T01:14:14Z
• Authors: Mingyu Liu; Shuolong Han; Qiaohong Liao; Liping Chang; Yunzhe Tan; Pingping Jia; Libo Yang; Hongbin Cai; Shaolun Feng; Can Chen; Shi Zhang; Zhenhua Jia; Jian Yi
• Keywords: 2019-20 coronavirus outbreak; Betacoronavirus

Since the first outbreak of coronavirus disease 2019 (COVID-19) occurred in December 2019, more than 51 million cases had been reported globally. We aimed to identify risk factors for in-hospital fatal outcome and severe pneumonia this disease. This is a retrospective, multicentre study, which included all confirmed COVID-19 with definite outcomes (died or discharged) hospitalized between 1 January 4 March 2020 Wuhan. Of 665 patients included, 70 died 595 discharged (including 333 mild 262 cases). Underlying comorbidity was commonly observed among deaths (72.9%) (26.4%) (61.5%) survivors, hypertension, diabetes cardiovascular as dominant diseases. Fever cough were primary clinical magnifications. Older age (≥65 years) (OR = 3.174, 95% CI 1.356-7.755), 2.540, 0.995-6.377), dyspnoea 7.478, 3.031-19.528), respiratory failure 10.528, 4.484-25.829), acute cardiac injury 25.103, 9.057-76.590) distress syndrome 7.308, 1.501-46.348) associated outcome. In addition, older 2.149, 1.424-3.248), 3.951, 2.077-7.788), 3.414, 1.432-8.799), nervous system 4.125, 1.252-18.681), 31.944, 18.877-92.741), achieving highest temperature >39.0°C 37.450, 7.402-683.403) longer onset illness diagnosis (≥9 days) statistically higher developing COVID-19. conclusion, potential forolder age, diabetes, dyspnoea, failure, could help clinicians poor prognosis at an early stage.