Prevalence and associated risk factors of Helicobacter pylori infection in the Wuwei cohort of north‐western China

• DOI: 10.1111/tmi.13517
• Publication Date: 2020-11-07T17:47:29Z
• Authors: Fuhua Zhang; Ke Pu; Zhengqi Wu; Zhiyi Zhang; Xin Liu; Zhaofeng Chen; Yuwei Ye; Yuping Wang; Ya Zheng; Jinhua Zhang; Feng An; Shijun Zhao; Xiaobin Hu; Youpeng Li; Qiang Li; Min Liu; Hong Lu; Hongling Zhang; Yue Zhao; Hao Yuan; Xiangping Ding; Xiaochuang Shu; Qian Ren; Xi Gou; Zenan Hu; Jun Wang; Yuling Wang; Quanlin Guan; Qinghong Guo; Rui Ji; Yongning Zhou
• Keywords: CagA

To evaluate the prevalence of Helicobacter pylori infection and risk factors to serotype strains in Wuwei, located north-western China, which has a high incidence gastric cancer. was analysed 21 291 adults by 14 C-urea breath test, H. antibody were detected 9183 serum samples latex immunoturbidimetric method. The correlation with demographic-economic, lifestyle medical history among participants determined questionnaire. antibodies against urease, VacA CagA dot immunobinding assay. rate 53.0%, 90.1% type I strains. higher farmers (OR = 1.34, 95% CI: 1.19-1.50) individuals who had junior school or education level 1.10, 1.06-1.15), lower older 0.86, 0.83-0.90), income 0.93, 0.90-0.95), habit eating quickly 0.87-0.99) consumed more fruit vegetables 0.90, 0.85-0.95). Individuals cholecystitis/cholecystolithiasis, hypertension asthma negatively correlated (P < 0.05). is Wuwei. major prevalent strain strain. Age, education, occupation, household income, consumption vegetables, are independent for infection, also associated extragastric diseases.