Diagnostic pitfalls of urogenital tuberculosis

• DOI: 10.1111/tmi.13583
• Publication Date: 2021-04-05T06:19:10Z
• Authors: Shruthi Chandran; Ananna Rahman; Joseph M. Norris; Simon Tiberi; Heinke Kunst
• Keywords: Urogenital tuberculosis

Abstract Objectives To describe characteristics, details of diagnosis and outcomes urogenital tuberculosis (UGTB) in a low‐prevalence country. Methods We conducted retrospective observational study 37 consecutive patients diagnosed with UGTB between 1 st January 2014 31 October 2019 an East London hospital. Results 68% (25/37) were male the median age was 42 years (IQR 34–55). 89% (33/37) born outside United Kingdom 65% (24/37) South Asian region. Renal (32.4%), epididymal (24.3%) endometrial TB (21.6%) most prevalent forms UGTB. Only 13.5% had concurrent pulmonary TB. The length time from symptom onset to treatment 163 days, while average delay 564 days. Approximately half culture positive (51.4%). However, 70% early morning urines (EMUs) sent urinary positive. 11 (30.6%) underwent two or more invasive procedures, such as biopsy obtain specimen samples. mean for all cases 7.3 months (SD 3.1). Notably, 25% required surgery despite antituberculous treatment. Conclusions is challenging diagnose disease often asymptomatic. Clinicians faced non‐specific symptoms, features suggestive malignancy amongst TB‐endemic areas, should maintain high suspicion