Outcomes of laboratory‐confirmed SARS‐CoV‐2 infection in the Omicron‐driven fourth wave compared with previous waves in the Western Cape Province, South Africa

• DOI: 10.1111/tmi.13752
• Publication Date: 2022-04-12T08:22:57Z
• Authors: Mary‐Ann Davies; Reshma Kassanjee; Petro Rousseau; Erna Morden; Leigh Johnson; Wesley Solomon; Nei‐Yuan Hsiao; Hannah Hussey; Graeme Meintjes; Masudah Paleker; Theuns Jacobs; Peter Raubenheimer; Alexa Heekes; Pierre Dane; Jamy‐Lee Bam; Mariette Smith; Wolfgang Preiser; David Pienaar; Marc Mendelson; Jonathan Naude; Neshaad Schrueder; Ayanda Mnguni; Sue Le Roux; Kathleen Murie; Hans Prozesky; Hassan Mahomed; Liezel Rossouw; Sean Wasserman; Deborah Maughan; Linda Boloko; Barry Smith; Jantjie Taljaard; Greg Symons; Ntobeko A. B. Ntusi; Arifa Parker; Nicole Wolter; Waasila Jassat; Cheryl Cohen; Richard Lessells; Robert J. Wilkinson; Juanita Arendse; Saadiq Kariem; Melvin Moodley; Milani Wolmarans; Keith Cloete; Andrew Boulle
• Keywords: Seroprevalence; Cape

The objective was to compare COVID-19 outcomes in the Omicron-driven fourth wave with prior waves Western Cape, assess contribution of undiagnosed infection differences a context high seroprevalence due and determine whether protection against severe disease conferred by and/or vaccination maintained.