Abscisic acid promotes proteasome‐mediated degradation of the transcription coactivator NPR1 in Arabidopsis thaliana

• DOI: 10.1111/tpj.13141
• Publication Date: 2016-02-11T04:26:59Z
• Authors: Yezhang Ding; Matthew Dommel; Zhonglin Mou
• Keywords: Degradation; Transcription

Summary Proteasome‐mediated turnover of the transcription coactivator NPR 1 is pivotal for efficient activation broad‐spectrum plant immune responses known as localized acquired resistance ( LAR ) and systemic (SAR) in adjacent tissues, respectively, requires CUL 3‐based E3 ligase its adaptor proteins, 3 4, which are receptors signaling molecule salicylic acid SA ). It has been shown that prevents under non‐inducing / SAR ‐inducing conditions, but how cellular homeostasis maintained remains unclear. Here, we show phytohormone abscisic ABA antagonistically influence protein levels. promotes degradation via 3/ 4 complex‐mediated proteasome pathway, whereas may protect from ‐promoted through phosphorylation. Furthermore, demonstrate timing strength critical modulating accumulation target gene expression. Perturbing or tissues alters temporal dynamic pattern transcription. Finally, sequential treatment leads to changes levels Our results revealed a tight correlation between 1‐dependent responses.