Two decades of risk factors and transfusion‐transmissible infections in Dutch blood donors

• DOI: 10.1111/trf.13298
• Publication Date: 2015-09-10T14:17:25Z
• Authors: Ed Slot; Mart P. Janssen; Tanneke Marijt‐va...; Hans L. Zaaijer; Thijs J. van de Laar
• Keywords: Residual risk; Hepatitis B

Risk behavior-based donor selection procedures are widely used to mitigate the risk of transfusion-transmissible infections (TTIs), but their effectiveness is disputed in countries with low residual risks TTIs.In 1995 2014, Dutch blood donors infected hepatitis B virus (HBV), C (HCV), human immunodeficiency (HIV), T-lymphotropic (HTLV), or syphilis were interviewed by trained medical counselors identify factors associated TTIs. Trends prevalence and incidence TTIs analyzed using binomial regression models.A total 972 new 381 repeat had New higher rates compared donors. Although HBV HCV gradually decreased over time, all five remained stable during past two decades. In following profiles: "blood-blood contact" for HCV, "unprotected sex" HIV syphilis, "country birth" HTLV. donors, sexual predominated At posttest counseling, 28% admitted leading permanent exclusion if revealed procedure (predominantly male-to-male sex recent diagnosis syphilis).The among six- 60-fold lower than general population, illustrating procedures. However, at least a quarter appeared noncompliant health questionnaire (DHQ), suggesting that DHQs, way questioning implemented, can be improved.