The evolving blood donor deferral policy for men who have sex with men: impact on the risk of HIV transmission by transfusion in France

• DOI: 10.1111/trf.15677
• Publication Date: 2020-02-06T11:58:31Z
• Authors: Josiane Pillonel; Camille Pelat; Pierre Tiberghien; Claire Sauvage; Bruno Danic; Christophe Martinaud; Francis Barin; Isabelle Sainte‐M...; Bruno Coignard; Sylvie Gross; Syria Laperche; Florence Lot
• Keywords: Deferral; Residual risk

Blood donation deferral for men who have sex with (MSM) in France was reduced from permanent to 12 months July 2016. To inform a further reduction of the period, an HIV risk assessment conducted two scenarios: S1, 4-month deferral; S2, only case more than one sexual partner (i.e., similar other blood donors).Baseline residual (RR) calculated 2016 December 2017, using Incidence Rate-Window Period method. The impact both scenarios on RR assessed data surveys MSM and donors, estimate 1) number additional expected donate each scenario 2) incidence among these donors.Baseline estimated at 1 6,380,000 donations. For 733 0.09 HIV-positive donations were estimated, yielding unchanged 6,300,000. numbers 3102 3.92, respectively, 4,300,000. Sensitivity analyses showed that, under worst-case assumptions, would equal 6,225,000 S1 3,000,000 S2.For scenarios, remains very low. is identical baseline RR. it 1.5 times higher, sensitivity analysis shows that this less robust S1. French Minister Health announced will be implemented April 2020.