Bariatric surgery prior to living donor nephrectomy: a solution to expand the living donor kidney pool – a retrospective study

• DOI: 10.1111/tri.13408
• Publication Date: 2019-02-05T18:53:04Z
• Authors: Minh‐Tri J. P. Ng...; Dustin Carpenter; Joseph Tadros; Abhishek Mathur; Pedro Rodrigo San...; E. Steve Woodle; Tayyab Diwan; Lloyd E. Ratner
• Keywords: Adult; Male; 2. Zero hunger; Bariatric Surgery; Middle Aged; Kidney Transplantation; Nephrectomy; Body Mass Index; Donor Selection; Obesity, Morbid; 3. Good health; 03 medical and health sciences; Postoperative Complications; Treatment Outcome; 0302 clinical medicine; Preoperative Period; Living Donors; Tissue and Organ Harvesting; Humans; Female; Laparoscopy; Postoperative Period; Retrospective Studies

Most transplant centers decline morbidly obese people for living kidney donation. Their inclusion in the living donor pool after weight loss and reversal of comorbidities by bariatric surgery could reverse the downward living donation trend. We investigated whether bariatric surgery in the morbidly obese altered their candidacy for donation, complicated their subsequent donor nephrectomy, and impacted their early postoperative outcomes in a series of 22 donors who had bariatric surgery 0.7-22 years prior to laparoscopic living donor nephrectomy. Eighteen would have been excluded from donation prior to bariatric surgery based on a body mass index (BMI) > 40. Seventeen reached a BMI < 35 after bariatric surgery. One had hypertension that resolved after bariatric surgery. Prior bariatric surgery did not influence port placement and laterality of donor nephrectomy. None required open conversion or blood transfusion. In an exploratory comparison with 37 donors with a BMI 35-40, length of stay and warm ischemic time were shorter, blood loss and postoperative complications were similar, and operative time was longer. We therefore advocate the consideration of bariatric surgery in preparation for donation in morbidly obese people since it positively alters their candidacy without major impact on the subsequent living donor nephrectomy and early outcomes.