Incidence and clinical characteristics of transfusion‐associated circulatory overload using an active surveillance algorithm

• DOI: 10.1111/vox.12466
• Publication Date: 2016-12-21T20:05:42Z
• Authors: N. H. Roubinian; J. E. Hendrickson; D. J. Triulzi; J. L. Gottschall; D. Chowdhury; D. J. Kor; M. R. Looney; M. A. Matthay; S. H. Kleinman; D. Brambilla; E. L. Murphy
• Keywords: Concordance

Background The concordance of haemovigilance criteria developed for surveillance transfusion‐associated circulatory overload ( TACO ) with its clinical diagnosis has not been assessed. In a pilot study to evaluate an electronic screening algorithm, we sought examine incidence and application in patients post‐transfusion pulmonary oedema. Study Design Methods From June September 2014, all transfused adult inpatients at four academic hospitals were screened algorithm identifying chest radiographs ordered within 12 h blood component release. Patients oedema underwent case adjudication by expert panel. was calculated, characteristics compared other causes Results Among 4932 patients, there 3412 alerts, 50 cases 47 1 per 100 transfused. classification based on two sets (National Healthcare Safety Network proposed revised International Society Blood Transfusion) concordant panel 57% 54% reviewed cases, respectively. Although the majority parameters did differentiate adjudicated from improved oxygenation 24 transfusion P = 0·01). Conclusions similar that observed prior studies utilizing active surveillance. Case frequently discordant diagnoses Improvements merit further evaluation .