A study of knowledge and acceptance of kidney xenotransplantation among Chinese kidney transplant recipients and candidates

• DOI: 10.1111/xen.12843
• Publication Date: 2024-02-26T16:38:48Z
• Authors: Yuhao Tu; Xiangli Zhao; Gang Chen; Lan Zhu
• Keywords: Xenotransplantation

Abstract Background In recent years, the implementation of first case pig‐to‐human heart xenotransplantation and report three cases pig‐to‐brain‐dead human recipient kidney transplantation indicate that is getting closer to clinical application. near future, China may also launch trials xenotransplantation. Therefore, it necessary investigate level knowledge acceptance among transplant recipients candidates in China. This study aims comprehension explore related factors, providing a reference for promoting application future. Methods A questionnaire was completed by 211 21 candidates. Answers questionnaires were self‐administered respondents. Scores compared using nonparametric tests, as well Chi‐square test or Fisher's exact compare differences answers. Results Respondents demonstrated high score 75 (out 100) on The sector “Knowledge Attitude” received overall highest from respondents (85.0 out 100), while “Risks Concerns” lowest (50 100). Interestingly, paid more attention infection risks but showed less concern about rejection unknown risks. Furthermore, 191 (82.3%) expected pig xenografts could function at least 5 years more. scores statistically significant terms age, gender, education, trial, willingness donate organs. cognition Conclusions awareness rates are candidates, which majority generally favorable attitude towards this procedure. did not have comprehensive understanding specific expressed risk other risks, expecting long‐term survival similar allograft xenografts.