Multichannel time domain fNIRS mapping of cortical activation and superficial systemic responses during neuromuscular electrical stimulation

• DOI: 10.1117/12.2032512
• Publication Date: 2013-06-24T15:30:46Z
• Authors: R. Re; M. Muthalib; L. Zucchelli; S. Perrey; D. Contini; M. Caffini; L. Spinelli; G. Kerr; A. Torricelli
• Keywords: time domain fNIRS; NMES; myostimulation; Time domain fNIRS; Statistical parametric mapping; cortical activation; Myostimul; Cortical activation; 01 natural sciences; Cortical imaging; 03 medical and health sciences; statistical parametric mapping; Blood oxygenation; 0302 clinical medicine; Sensorimotor; blood oxygenation; 0103 physical sciences; cor; Myostimulation; sensorimotor

We recorded maps of cortical and systemic hemodynamic responses (oxy-hemoglobin, O2Hb and deoxy-hemoglobin, HHb) during incremental neuromuscular electrical stimulation (NMES) of the right forearm in nine subjects by a 32- channel time domain fNIRS (TD-fNIRS) instrument. Statistical parametric maps (SPM) relative to the different current stimulations (under and over the maximal tolerated intensity-MTI) versus the 10%MTI were generated. Exploiting the temporal information contained in the TD-fNIRS signal it was possible to create different maps referring to the deeper (cortical activations) and the more superficial (systemic changes) head layers. The increasing of the stimulation current on the right forearm muscle produced a significantly larger bilateral sensorimotor and prefrontal cortical activations (i.e. increase in the O2Hb and decrease in HHb) than the systemic changes. Physiological parameters (heart rate, breathing rate and skin conductance) were also monitored.