Comparison of radiograph‐based texture analysis and bone mineral density with three‐dimensional microarchitecture of trabecular bone

• DOI: 10.1118/1.3528125
• Publication Date: 2010-12-31T01:51:59Z
• Authors: P. Ranjanomennahary; S. Sevestre Ghalila; D Malouche; A. Marchadier; M. Rachidi; Cl. Benhamou; C. Chappard
• Keywords: Cadaveric spasm; Region of interest

Purpose: Hip fracture is a serious health problem and textural methods are being developed to assess bone quality. The authors aimed perform analysis at femur on high‐resolution digital radiographs compared three‐dimensional (3D) microarchitecture comparatively mineral density. Methods: Sixteen cadaveric femurs were imaged with an x‐ray device using C‐MOS sensor. One 17 mm square region of interest (ROI) was selected in the femoral head (FH) one great trochanter (GT). Two‐dimensional (2D) features from co‐occurrence matrices extracted. Site‐matched measurements density performed. Inside each ROI, 16 diameter core Apparent volume proportion measured defatted Archimedes' principle. Microcomputed tomography images entire length obtained (Skyscan 1072®) resolution usual 3D morphometric parameters computed binary after calibration . Then, surface/bone volume, trabecular thickness, separation, number by direct without model assumption structure index calculated. Results: In univariate analysis, correlation coefficients between 2D morphological reached 0.83 FH 0.79 GT. multivariate canonical first component 0.95 0.88 Conclusions: Digital radiographs, widely available economically viable, alternative method for evaluating microarchitectural structure.