SU‐F‐T‐50: Evaluation of Monte Carlo Simulations Performance for Pediatric Brachytherapy Dosimetry

• DOI: 10.1118/1.4956185
• Publication Date: 2016-07-05T20:55:41Z
• Authors: C Chatzipapas; P Papadimitroulas; G Loudos; N Papanikolaou; G Kagadis
• Keywords: Dose rate

Purpose: Pediatric tumors are generally treated with multi‐modal procedures. Brachytherapy can be used pediatric tumors, especially given that in this patient population low toxicity on normal tissues is critical as the suppression of probability for late malignancies. Our goal to validate GATE toolkit realistic brachytherapy applications, and evaluate plans pediatrics accurate dosimetry sensitive organs interest. Methods: The Monte Carlo (MC) was used. Two High Dose Rate (HDR) 192Ir sources were simulated (Nucletron mHDR‐v1 Varian VS2000), fully validated using AAPM ESTRO protocols. A plan also XCAT anthropomorphic computational model .The data compared clinical dose points. Finally, a 14 years old girl vaginal rhabdomyosarcoma modelled based procedures calculation absorbed per organ. Results: MC simulations resulted terms rate constant (Λ), radial gL(r) anisotropy function F(r,θ) both sources.The executed ∼1010 number primaries resulting statistical uncertainties lower than 2%.The differences between theoretical values ones ranged from 0.01% up 3.3%, largest discrepancy (6%) being observed calculation.The DVH an adult female one smaller 5%. simulation performed organ calculate respect heterogeneities human anatomy. Conclusion: reliable tool source modeling voxelized models. project aims variety schemes phantoms several pathological cases. This study part has received funding European Union Horizon2020 research innovation programme under MarieSklodowska‐Curiegrantagreement.No691203.The results published reflect only authors view Research Executive Agency (REA) Commission not responsible any use may madeof information it contains.