Passive imaging with pulsed ultrasound insonations

• DOI: 10.1121/1.4728230
• Publication Date: 2012-07-11T22:58:50Z
• Authors: Kevin J. Haworth; T. Douglas Mast; Kirthi Radhakrishnan; Mark T. Burgess; Jonathan A. Kopechek; Shao-Ling Huang; David D. McPherson; Christy K. Holland
• Keywords: Envelope (radar); Echogenicity

Previously, passive cavitation imaging has been described in the context of continuous-wave high-intensity focused ultrasound thermal ablation. However, technique potential use as a feedback mechanism for pulsed-wave therapies, such ultrasound-mediated drug delivery. In this paper, results experiments and simulations are reported to demonstrate feasibility using pulsed insonations how images depend on parameters. The were formed from channel data that was beamformed frequency domain. Experiments performed an invitro flow phantom with experimental echo contrast agent, echogenic liposomes, nuclei. It found pulse duration envelope have minimal impact image resolution achieved. amplitude scales linearly emission energy. Cavitation both stable inertial can be obtained same received set.