The PTEN pathway in T regs is a critical driver of the suppressive tumor microenvironment

PTEN indoleamine 2,3-dioxygenase SciAdv r-articles 610 Tregs Regulatory T cells Cancer Immunotherapy 3. Good health 03 medical and health sciences 0302 clinical medicine tumor microenvironment tumor immunology 14. Life underwater Research Articles
DOI: 10.1126/sciadv.1500845 Publication Date: 2015-11-07T04:09:27Z
ABSTRACT
Tumors depend on a specialized pathway of regulatory T cell activation to create their immunosuppressive microenvironment, which can be blocked by inhibiting PTEN phosphatase.
SUPPLEMENTAL MATERIAL
Coming soon ....
REFERENCES (68)
CITATIONS (157)
EXTERNAL LINKS
PlumX Metrics
RECOMMENDATIONS
FAIR ASSESSMENT
Coming soon ....
JUPYTER LAB
Coming soon ....