Mannan-induced Nos2 in macrophages enhances IL-17–driven psoriatic arthritis by innate lymphocytes

0301 basic medicine Lipopolysaccharide Receptors 610 Gene Expression Nitric Oxide Synthase Type II Mice, Transgenic Nitric Oxide Mannans Mice 03 medical and health sciences T-Lymphocyte Subsets Interleukin-1alpha Animals Humans ddc:610 Lymphocytes Research Articles Alleles ddc:610 0303 health sciences Macrophages Arthritis, Psoriatic Interleukin-17 Immunity, Innate 3. Good health Disease Models, Animal 13. Climate action
DOI: 10.1126/sciadv.aas9864 Publication Date: 2018-05-16T18:15:14Z
ABSTRACT
Inducible nitric oxide from skin macrophages promotes IL-17 release and psoriatic arthritis by innate lymphoid cells.
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