Biophysical and biomolecular interactions of malaria-infected erythrocytes in engineered human capillaries

• DOI: 10.1126/sciadv.aay7243
• Publication Date: 2020-01-18T00:16:00Z
• Authors: Christopher Arakawa; Celina Gunnarsson; Caitlin Howard; Maria Bernabeu; Kiet Phong; Eric Yang; Cole A. DeForest; Joseph D. Smith; Ying Zheng
• Keywords: 0301 basic medicine; Erythrocytes; Light; Tissue Engineering; Plasmodium falciparum; Ligands; Biophysical Phenomena; Capillaries; Malaria; 3. Good health; Perfusion; 03 medical and health sciences; Hematocrit; Cell Movement; Cell Adhesion; Human Umbilical Vein Endothelial Cells; Humans; Collagen; Research Articles

Engineered human capillaries reveal distinct contributions of hemodynamics and cytoadhesion in malaria parasite sequestration.