Irradiated tumor cell–derived microparticles mediate tumor eradication via cell killing and immune reprogramming

• DOI: 10.1126/sciadv.aay9789
• Publication Date: 2020-03-25T23:14:36Z
• Authors: Chao Wan; Yajie Sun; Yu Tian; Lisen Lu; Xiaomeng Dai; Jingshu Meng; Jing Huang; Qianyuan He; Bian Wu; Zhanjie Zhang; Ke Jiang; Desheng Hu; Gang Wu; Jonathan F. Lovell; Honglin Jin; Kunyu Yang
• Keywords: Reprogramming

By mimicking the RIBE machinery, we provided an indirect radiotherapy approach based on RT-MP for eradication of MPE in mice.