Disruption in ACTL7A causes acrosomal ultrastructural defects in human and mouse sperm as a novel male factor inducing early embryonic arrest

• DOI: 10.1126/sciadv.aaz4796
• Publication Date: 2020-08-28T23:53:33Z
• Authors: Aijie Xin; Ronggui Qu; Guowu Chen; Ling Zhang; Junling Chen; Chengqiu Tao; Jing Fu; Jianan Tang; Yanfei Ru; Ying Chen; Xiandong Peng; Huijuan Shi; Feng Zhang; Xiaoxi Sun
• Keywords: 0301 basic medicine; 03 medical and health sciences; Research Articles

ACTL7A deficiency is a novel male factor inducing early embryonic arrest that can be overcome by artificial oocyte activation.