Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects
Base (topology)
Substitution (logic)
APOBEC3G
DOI:
10.1126/sciadv.aba1773
Publication Date:
2020-07-15T23:15:56Z
AUTHORS (13)
ABSTRACT
Engineered base editors convert the second nucleotide C to T in context of 5′-CC-3′ with high precision and targeting fidelity.
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CITATIONS (69)
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