Development of a potent Zika virus vaccine using self-amplifying messenger RNA

• DOI: 10.1126/sciadv.aba5068
• Publication Date: 2020-08-07T23:19:12Z
• Authors: Kate Luisi; Kaitlyn M. Morabito; Katherine E. Burg...; Mayuri Sharma; Wing-Pui Kong; Bryant M. Foreman; Sonal Patel; Brian Fisher; Maya A. Aleshnick; Jason Laliberte; Madison Wallace; Tracy J. Ruckwardt; David N. Gordon; Christine Linton; Nicole Ruggiero; Jessica L. Cohen; Russell Johnson; Kunal Aggarwal; Sung-Youl Ko; Eun Sung Yang; Rebecca S. Pelc; Kimberly A. Dowd; Derek O’Hagan; Jeffrey Ulmer; Sally Mossman; Anna Sambor; Edith Lepine; John R. Mascola; Theodore C. Pierson; Barney S. Graham; Dong Yu
• Keywords: Zika Virus

A Zika self-amplifying mRNA vaccine delivered by a flexible bedside mixing formulation induces protective immunity in NHPs.