The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes

• DOI: 10.1126/sciadv.abc7209
• Publication Date: 2020-12-16T21:43:25Z
• Authors: Meng Lu; Francesca W. van ...; Julie Qiaojin Lin; Wilco Nijenhuis; Pierre Parutto; Marcus Fantham; Charles N. Christ...; Edward Avezov; Christine E. Holt; Alan Tunnacliffe; David Holcman; Lukas Kapitein; Gabriele S. Kamin...; Clemens F. Kaminski
• Keywords: 0301 basic medicine; 0303 health sciences; 03 medical and health sciences; 2.1 Biological and endogenous factors; Generic health relevance; 3101 Biochemistry and Cell Biology; Research Articles; 31 Biological Sciences

Lysosomes, important centers of metabolic sensing and material recycling, play a key role in the dynamic reshaping of the ER.