Agonist anti-ChemR23 mAb reduces tissue neutrophil accumulation and triggers chronic inflammation resolution

• DOI: 10.1126/sciadv.abd1453
• Publication Date: 2021-04-02T19:10:36Z
• Authors: C. Trilleaud; V. Gauttier; K. Biteau; I. Girault; L. Belarif; C. Mary; S. Pengam; G. Teppaz; V. Thepenier; R. Danger; G. Robert-Siegwald; M. Néel; S. Bruneau; A. Glémain; A. Néel; A. Poupon; J. F. Mosnier; G. Chêne; M. Dubourdeau; G. Blancho; B. Vanhove; N. Poirier
• Keywords: MESH: Inflammation; 0301 basic medicine; Neutrophils; [SDV]Life Sciences [q-bio]; 610; MESH: Neutrophils; Inbred C57BL; Mice; 03 medical and health sciences; MESH: Mice, Inbred C57BL; MESH: Receptors; Animals; Humans; MESH: Animals; MESH: Mice; Research Articles; Inflammation; MESH: Humans; MESH: Inflammatory Bowel Diseases; Inflammatory Bowel Diseases; 3. Good health; [SDV] Life Sciences [q-bio]; Mice, Inbred C57BL; Chemokine; Receptors, Chemokine; MESH: Receptors, Chemokine

Agonistic proresolutive monoclonal antibody reverses chronic inflammation.