Nanotransfection-based vasculogenic cell reprogramming drives functional recovery in a mouse model of ischemic stroke

• DOI: 10.1126/sciadv.abd4735
• Publication Date: 2021-03-19T19:21:56Z
• Authors: Luke R. Lemmerman; Maria H. H. Balch; Jordan T. Moore; Diego Alzate-Correa; Maria A. Rincon-B...; Ana Salazar-Puerta; Surya Gnyawali; Hallie N. Harris; William Lawrence; Lilibeth Ortega-P...; Lauren Wilch; Ian B. Risser; Aidan J. Maxwell; Silvia Duarte-San...; Daniel Dodd; Gina P. Guio-Vega; Dana M. McTigue; W. David Arnold; Shahid M. Nimjee; Chandan K. Sen; Savita Khanna; Cameron Rink; Natalia Higuita-C...; Daniel Gallego-Perez
• Keywords: Reprogramming; Stroke

Fibroblasts nonvirally programmed to convert into induced endothelial cells show therapeutic potential for ischemic stroke.