Cardiac cell type–specific gene regulatory programs and disease risk association

• DOI: 10.1126/sciadv.abf1444
• Publication Date: 2021-05-14T19:16:11Z
• Authors: James D. Hocker; Olivier B. Poirion; Fugui Zhu; Justin Buchanan; Kai Zhang; Joshua Chiou; Tsui-Min Wang; Qingquan Zhang; Xiaomeng Hou; Yang E. Li; Yanxiao Zhang; Elie N. Farah; Allen Wang; Andrew D. McCulloch; Kyle J. Gaulton; Bing Ren; Neil C. Chi; Sebastian Preissl
• Keywords: 0301 basic medicine; 0303 health sciences; Nucleic Acid; Human Genome; 610; Heart; Regulatory Sequences, Nucleic Acid; Cardiovascular; 3. Good health; Promoter Regions; 03 medical and health sciences; Heart Disease; Good Health and Well Being; Genetic; Genetics; 2.1 Biological and endogenous factors; Humans; Aetiology; Promoter Regions, Genetic; Regulatory Sequences; Research Articles; Biotechnology; Transcription Factors

A human heart cell type–specific cis-regulatory element atlas reveals gene regulatory mechanisms of cardiovascular diseases.