Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

• DOI: 10.1126/sciadv.abf9141
• Publication Date: 2021-06-04T19:19:58Z
• Authors: Valentin J. A. Ba...; Martina Brucoli; Marcus J. G. W. L...; Christoph Nössing; Christos Kiourtis; Alice D. Baudot; James O’Prey; Barbara Zunino; Miryam Müller; Stephanie May; Colin Nixon; Jaclyn S. Long; Thomas G. Bird; Kevin M. Ryan
• Keywords: Progenitor; Liver Cancer

Autophagy represses YAP/TAZ-dependent hepatocyte dedifferentiation into liver progenitor cells to prevent tumorigenesis.