Minimally instrumented SHERLOCK (miSHERLOCK) for CRISPR-based point-of-care diagnosis of SARS-CoV-2 and emerging variants

• DOI: 10.1126/sciadv.abh2944
• Publication Date: 2021-08-06T19:06:30Z
• Authors: Helena de Puig; Rose A. Lee; Devora Najjar; Xiao Tan; Luis R. Soenksen; Nicolaas M. Angen...; Nina M. Donghia; Nicole E. Weckman; Audrey Ory; Carlos F. Ng; Peter Q. Nguyen; Angelo S. Mao; Thomas C. Ferrante; Geoffrey Lansberry; Hani Sallum; James Niemi; James J. Collins
• Keywords: 2019-20 coronavirus outbreak; Point of care

An integrated, low-cost, sample-to-answer, CRISPR-based diagnostic detects SARS-CoV-2 and variants from unprocessed saliva.